目的 :探讨小儿无症状性室性早搏 (VPC)的昼夜变化规律与自主神经功能状态的关系及其临床意义。方法 :对30例无症状性VPC患儿进行 2 4小时动态心电图 (DCG)监测 ,自主神经功能及心室晚电位检查。结果 :13/30例 (4 3 % )为日间型VPC ,10 /30 (30 % )为夜间型VPC。 13例日间型中 ,12例属交感性VPC ,10例夜间型均属迷走性VPC。日间型VPC频率与心率呈正相关 (r =0 .6 7,P <0 .0 5 ) ,夜间型VPC频率与心率呈负相关 (r =- 0 .6 9,P <0 .0 5 ) ,本组 2 0例做心室晚电位检查均正常 ,未发现器质性心脏病。结论 :无症状性VPC日间型可能是交感神经张力增高所致 ;而夜间型与迷走神经张力增高有关 ,此类无症状性VPC一般预后良好 Objective: To investigate the relationship between circadian rhythm of asymptomatic ventricular premature beats (VPC) and autonomic nerve function in children and its clinical significance. METHODS: Twenty-four children with asymptomatic VPC underwent 24-hour ambulatory electrocardiogram (DCG) monitoring, autonomic nerve function and ventricular late potentials. Results: 13/30 (43%) were daytime VPC and 10/30 (30%) nighttime VPC. Among 13 cases of daytime type, 12 cases were sympathetic VPC, and 10 cases were nocturnal VPC. Daytime VPC frequency was positively correlated with heart rate (r = 0.67, P <0.05), nighttime VPC frequency was negatively correlated with heart rate (r = -0.696, P <0.05) , The group of 20 cases of ventricular late potentials were normal, did not find organic heart disease. CONCLUSIONS: Asymptomatic VPC daytime patterns may be due to increased sympathetic tone, whereas nighttime patterns are associated with increased vagal tone, and these asymptomatic VPCs generally have a good prognosis