论文部分内容阅读
目的探讨功能磁共振弥散成像技术(DWI)+质子波谱分析技术(1HMRS)联合应用于早期急性放射性脑损伤的诊断。方法应用1·5T磁共振机的弥散成像技术+质子波谱分析技术对2例鼻咽癌病人在放疗前和放疗结束进行顶叶、颞叶扫描。结果放疗前,DWI成像2例病人未见异常,1HMRS扫描顶叶和颞叶的NAA、Cr、Cho在正常范围,放疗结束,DWI成像显示两侧颞叶脑深部不规则高信号影,DWI扫描,顶叶NAA、Cr、Cho在正常范围,颞叶A例NAA、Cr、Cho分别为25·46、30·18、55·17,B例的NAA、Cr、Cho分别为26·47、30·13、56·03。与放疗前比较,颞叶的DWI和1HMRS都呈现病理性影像学表现。结论功能磁共振弥散成像技术(DWI)+质子波谱分析技术(1HMRS)联合应用可以在影像学上反映早期急性放射性脑损伤。
Objective To investigate the combined application of diffusion-weighted magnetic resonance imaging (DWI) and proton magnetic resonance spectroscopy (1HMRS) in early diagnosis of acute radiation-induced brain injury. Methods 2 patients with nasopharyngeal carcinoma were treated with diffusion imaging and proton spectroscopy of 1.5T magnetic resonance imaging before and at the end of radiotherapy. Results Before radiotherapy, there were no abnormalities in DWI imaging in 2 patients. NAA, Cr and Cho in the parietal lobe and temporal lobe of 1H MRS were in the normal range and the end of radiotherapy was completed. DWI imaging revealed irregular high signal intensity in both temporal lobe and DWI , NAA, Cr, Cho in the parietal lobe NAA, Cr, Cho were 25.46,30.18, 55.17 respectively in the A region of the temporal lobe, NAA, Cr, Cho were 26.47, · 13,56 · 03. Compared with the pre-radiotherapy, temporal lobe DWI and 1HMRS showed pathological imaging findings. Conclusion The combination of DWI + 1HMRS can reflect the early stage of acute radiation-induced brain injury.