了解百春肝泰灵对小鼠免疫性肝损伤及免疫功能的影响。方法采用丙酸杆菌（ＣＰ）加脂多糖（ＬＰＳ）诱导小鼠免疫性肝损伤模型和环磷酰胺（Ｃｙ）所致小鼠ＤＴＨ反应增高模型进行观察。结果百春肝泰灵（３、９、２７ｇ·ｋｇ－１，ｑｄ×１０ｄ，ｉｇ）可使免疫性肝损伤小鼠升高的血清ＡＬＴ、ＡＳＴ和肝脏指数降低（Ｐ＜０．０１），并使小鼠肝脏损伤性病理变化减轻；同时能使Ｃｙ所致小鼠增高的ＤＴＨ反应及Ｔ淋巴细胞增殖反应降低（Ｐ＜０．０１）。结论百春肝泰灵对小鼠免疫性肝损伤有明显的保护作用 To understand the effect of Bai Chun Gan Tai Ling on immune liver injury and immune function in mice. Methods The model of immunological liver injury induced by Propionibacterium acylglucose (CP) plus lipopolysaccharide (LPS) and the model of DTH induced by Cyclophosphamide (Cy) were observed. Results Baixian liver Tailing (3,9,27g · kg-1, qd × 10d, ig) could reduce serum ALT, AST and liver index (P <0.01) And lessened the pathological changes of liver injury in mice. At the same time, DTH response and T lymphocyte proliferation response in mice induced by Cy decreased (P <0.01). Conclusion Bai Chun Gan Tai Ling on mice with immunological liver injury has a significant protective effect