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目的：探讨急性盆腔炎患者血清白细胞介素２（ＩＬ２）、可溶性白细胞介素２受体（ｓＩＬ２Ｒ）、肿瘤坏死因子（ＴＮＦ）水平的临床意义。方法：以４０例急性盆腔炎患者为对象与２０名健康人、５９例子宫肌瘤患者为对照，采取一步法竞争性放射免疫测定ＩＬ２，双抗体夹心酶联免疫吸附试验（ＥＬＩＳＡ）测定ｓＩＬ２Ｒ，生物学测定法测定ＴＮＦ。结果：急性盆腔炎患者ｓＩＬ２Ｒ水平明显高于健康人组（Ｐ＜０．０５）和子宫肌瘤组（Ｐ＜０．０１）；ＴＮＦ水平明显高于健康人组（Ｐ＜０．０５）。提示ｓＩＬ２Ｒ及ＴＮＦ可间接反映急性盆腔炎时感染程度。
Objective: To investigate the clinical significance of serum interleukin 2 (IL 2), soluble interleukin 2 receptor (sIL2R) and tumor necrosis factor (TNF) in patients with acute pelvic inflammatory disease. Methods: Forty patients with acute pelvic inflammatory disease were selected and compared with 20 healthy individuals and 59 patients with uterine leiomyoma. One-step competitive radioimmunoassay (IL-2) was used to determine IL-2, and sIL2R was detected by double antibody sandwich enzyme-linked immunosorbent assay Biological assays determine TNF. Results: The level of sIL2R in patients with acute pelvic inflammatory disease was significantly higher than that in healthy people (P <0.05) and uterine fibroids (P <0.01). The levels of TNF in patients with acute pelvic inflammatory disease were significantly higher than those in healthy people (P <0.05). Tip sIL2R and TNF may indirectly reflect the degree of acute pelvic inflammatory disease infection.