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化疗药物的进展及其联合方案的实施,使急性白血病(AL)的完全缓解(CR)率有很大的提高;中枢神经系统白血病(CNSL)的预防使AL的缓解期显著延长。但要治愈AL,白血病的睾丸浸润就成了毋容忽视的重要课题。本文就此作一综述。一、发生率白血病性睾丸浸润(简称,TL)的发生率各家报道不一。在AL确诊时临床上发生TL者仅零星个案,Hustu等报道病程中发生TL的25例患者仅1例发生于确诊时;病程中TL发生率8-10.7%;CR期间单一的TL复发的发生率5.9-16%。英国儿童白血病组急性淋巴细胞白血病(ALL)
The progress of chemotherapeutic drugs and the implementation of the combination regimen greatly improved the rate of complete remission (CR) in acute leukemia (AL). The prevention of central nervous system leukemia (CNSL) significantly prolonged the remission period of AL. But to cure AL, testicular infiltration of leukemia has become an important issue that can not be ignored. This article gives a summary of this. First, the incidence of leukemia testis infiltration (referred to as, TL) incidence of various reports vary. TL was only sporadic cases when AL was diagnosed clinically. Only one case of 25 patients with TL occurred during the course of Hustu et al reported that the incidence of TL was 8-10.7% during the course of disease. A single TL recurrence occurred during CR 5.9-16% rate. British childhood leukemia group Acute lymphoblastic leukemia (ALL)