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用浮置微电极技术观察垂体后叶素（Ｐｉｔ）对兔心肌细胞的异常电生理学效应及降钙素基因相关肽（ＣＧＲＰ）的保护作用。结果表明：静脉注射Ｐｉｔ后，心率减慢，心外膜电图ＳＴ段抬高，Ｔ波倒置，心室肌细胞跨膜动作电位（ＴＭＰ）的静息电位（ＲＰ）及动作电位振幅（ＡＰＡ）明显降低（Ｐ均＜０．０１）。复极化至３０％、５０％和９０％的动作电位时程（ＡＰＤ３０、ＡＰＤ５０、ＡＰＤ９０）亦明显缩短（Ｐ均＜０．０５）。静脉注射Ｐｉｔ同时注射ＣＧＲＰ，可见ＣＧＲＰ明显拮抗以上异常改变，从而起到保护心肌和稳定心肌的电生理作用。
Floating microelectrode technique was used to observe the abnormal electrophysiological effects of pituitary pit on rabbit cardiomyocytes and the protective effect of calcitonin gene-related peptide (CGRP). The results showed that: after intravenous injection of Pit, heart rate slowed down, ST segment elevation in epicardial electrogram, T wave inversion, ventricular resting potential (RP) and action potential amplitude (APA) in ventricular myocytes transmembrane action potential (TMP) Significantly lower (P <0.01). Polarization to 30%, 50% and 90% of the action potential duration (APD30, APD50, APD90) also significantly shortened (P all <0.05). Intravenous injection of CGRP at the same time, we can see CGRP significantly antagonized the above abnormal changes, which play to protect the myocardium and myocardial electrophysiological stability.