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目的对比分析酮康唑单独及联合克霉唑栓治疗老年念球菌性阴道炎的疗效。方法 68例老年念球菌性阴道炎患者,随机分为对照组和研究组,各34例。对照组单独给予酮康唑治疗,研究组给予酮康唑联合克霉唑栓治疗,对比分析两组患者的临床治疗效果。结果研究组总显效率(100.00%)优于对照组(85.29%),且前者起效时间、复发率均优于对照组(P<0.05)。两组不良反应均较轻,对预后无太大影响。结论酮康唑联合克霉唑栓治疗老年念球菌性阴道炎的疗效显著,且安全性较高,值得在临床推广应用。
Objective To compare the efficacy of ketoconazole alone and in combination with clotrimazole suppositories for the treatment of elderly candidal vaginitis. Methods Sixty-eight elderly patients with candidal vaginitis were randomly divided into control group and study group, with 34 cases in each group. The control group was treated with ketoconazole alone. The study group was given ketoconazole combined with clotrimazole suppositories, and the clinical effects of the two groups were compared. Results The total effective rate (100.00%) in the study group was better than that in the control group (85.29%), and the onset time and recurrence rate of the former group were better than those of the control group (P <0.05). Two groups of adverse reactions were mild, no significant effect on the prognosis. Conclusion The efficacy of ketoconazole combined with clotrimazole suppositories for the treatment of elderly candidal vaginitis is significant and safe. It is worthy of clinical application.