【摘 要】
:
A new, convenient and excellent yield procedure for the preparation of bis(indolyl)methanes(BIMs) by Friedel–Crafts reaction of indoles with imines in the pres
【机 构】
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Key Laboratory of Oil & Gas Fine Chemicals,Ministry of Education & Xinjiang Uyghur Autonomous Region
【出 处】
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Chinese Chemical Letters
论文部分内容阅读
A new, convenient and excellent yield procedure for the preparation of bis(indolyl)methanes(BIMs) by Friedel–Crafts reaction of indoles with imines in the presence of dithiocarbohydrazone Schiff base/ Zn(ClO4)2 6H2 O as a highly stable, effective and readily available catalyst is described. Moderate to good yields(up to 99% yield) were obtained with both substrates for imine derivatives. This procedure is simple, practical and economic.
A new, convenient and excellent yield procedure for the preparation of bis (indolyl) methanes (BIMs) by Friedel-Crafts reaction of indoles with imines in the presence of dithiocarbohydrazone Schiff base / Zn (ClO4) 2 6H2 O as a highly stable, effective Moderate to good yields (up to 99% yield) were obtained with both substrates for imine derivatives. This procedure is simple, practical and economic.
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