采用大鼠游离原代肝细胞培养技术,观察肝细胞对cd的吸收及cd对肝细胞内钙稳态的影响。实验发现,肝细胞对cd的吸收分为两个时期,即迅速吸收期和缓慢吸收期。在cd作用浓度为3.56μmol/L时,肝细胞内钙稳态并未发生明显变化;与此同时,肝细胞内CaM与Ca~(2+)-Mg~(2+)-ATP酶活性 Rat free primary hepatocyte culture technique was used to observe the uptake of Cd by hepatocytes and the effect of Cd on the intracellular calcium homeostasis. The experiment found that the absorption of cd into hepatocytes is divided into two periods, namely the rapid absorption period and the slow absorption period. At the concentration of 3.56μmol / L, the intracellular calcium homeostasis did not change significantly. At the same time, the intracellular CaM and Ca ~ (2 +) - Mg ~ (2 +) - ATPase activity