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目的本文旨在探讨泉州市丙型病毒性肝炎(丙肝)发病趋势和流行病学特征,为制定防控策略提供科学依据。方法研究采用描述流行病学方法对泉州市1990-2011年丙肝监测资料进行分析。结果 1990-2011年共报告丙肝1 241例,平均年发病率为0.83/10万,发病率呈逐年上升趋势(χ2趋势=1 351.78,P<0.001);中心市区平均年发病率高于沿海地区(χ2=55.71,P<0.001),沿海地区平均年发病率高于山区(χ2=43.72,P<0.001);每月均有病例发生,无明显的季节分布;丙肝发病以20~39岁青壮年为主,发病率随年龄的增加而逐渐上升(χ2趋势=412.63,P<0.001);男性发病率高于女性(χ2=45.24,P<0.001);职业以农民、家务及待业、工人为主。结论泉州市丙肝发病率总体较低,但呈明显上升趋势,需加强控制工作,建立以切断传播途径为主的综合防控措施。
Objective This article aims to investigate the trend and epidemiological characteristics of hepatitis C virus in Quanzhou and provide a scientific basis for the development of prevention and control strategies. Methods The descriptive epidemiological method was used to analyze data of hepatitis C surveillance in Quanzhou from 1990 to 2011. Results A total of 1 241 hepatitis C cases were reported from 1990 to 2011, with an average annual incidence rate of 0.83 per 100 000. The incidence rate showed an upward trend year by year (χ2 trend = 1 351.78, P <0.001). The average annual incidence rate of urban centers was higher than that of coastal areas (Χ2 = 55.71, P <0.001). The average annual incidence rate in coastal areas was higher than that in mountainous areas (χ2 = 43.72, P <0.001). There were monthly cases with no obvious seasonal distribution. (Χ2 = 412.63, P <0.001). The incidence of males was higher than that of females (χ2 = 45.24, P <0.001). The occupations were peasants, housework and unemployed workers Mainly. Conclusion The incidence of hepatitis C in Quanzhou is generally low, but it shows a clear upward trend. It is necessary to strengthen the control work and establish a comprehensive prevention and control measures that mainly cut off the route of transmission.