严重急性呼吸综合征(SAKS)是一种影响全球的新型传染病。虽已确定冠状病毒家族中一病毒为其病因,但该病的发病机制仍不清楚,作者报告6例死于SARS患者的病理学和病毒学结果。 方法 研究对象为2003年2月至3月期间因SARS死亡的6例患者。6例均符合WHO修订的SARS诊断标准并有肺活检或死后检查。疾病定义为有发热(体温≥38℃)、咳嗽或 Severe Acute Respiratory Syndrome (SAKS) is a new type of infectious disease that affects the world. Although a virus in the coronavirus family has been identified as its cause, the pathogenesis of this disease is still unclear. The authors reported the pathology and virology of 6 patients who died of SARS. Methods Subjects were 6 patients died of SARS during February to March 2003. Six cases were in line with WHO revised SARS diagnostic criteria and lung biopsy or post-mortem examination. Disease is defined as fever (body temperature ≥38 ℃), cough or