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目的在凉山州孕产妇人群中开展1型艾滋病病毒(HIV-1)新发感染检测,并估算该人群的HIV-1感染率和新发感染率,了解凉山州2011-2015年孕产妇人群HIV-1感染状况及防控策略探讨。方法用BED捕获酶免疫技术检测2011-2015年3个孕产妇哨点采集的HIV确证阳性样本,计算HIV-1在该人群中的感染率,并估算新发感染率,采用!2检验进行统计分析。结果 2011-2015年共对5486例血样进行HIV-1抗体筛查,确证阳性243例,HIV-1感染率4.43%;新发感染24例,新发感染率1.13%[95%可信区间(CI):0.68~1.59]。!2趋势检验得到各年度新发感染率差异无统计学意义(!2=2.235,P=0.135)。结论 2011-2015年,凉山州孕产妇HIV-1感染率及新发感染率均处于较高水平,需进一步加强孕产妇人群的行为干预和监测工作。
Objective To carry out the detection of new HIV-1 infection in pregnant women in Liangshan Prefecture and estimate the prevalence of HIV-1 infection and new infection in this population. To understand the prevalence of HIV-1 in 2011-2015 among pregnant women in Liangshan Prefecture. -1 infection and prevention and control strategies. Methods The HIV-positive samples collected from 3 pregnant women sentinel sites in 2011-2015 were detected by BED-capture enzyme immunoassay. The infection rate of HIV-1 in this population was calculated and the incidence of new infections was estimated. The 2-test was used for statistics analysis. Results A total of 5486 blood samples were screened for HIV-1 antibody in 2011-2015, of which 243 were confirmed positive and the prevalence of HIV-1 infection was 4.43%. There were 24 new infections and 1.13% of new infections (95% CI [95% confidence interval CI): 0.68 ~ 1.59]. 2 trend test to get the annual incidence of new infections was no significant difference (! 2 = 2.235, P = 0.135). Conclusion From 2011 to 2015, the HIV-1 infection rate and new infection rate among pregnant women in Liangshan Prefecture are at a high level, so it is necessary to further strengthen behavioral intervention and monitoring of pregnant women.