论文部分内容阅读
目的评价胃肠道来源肺转移瘤CT导向下125I粒子植入治疗的短期疗效。方法20例胃肠道来源肺转移瘤患者,肺内病灶5个以下,总计病灶数56个,平均每例2.8个病灶,病灶平均直径2.1cm(0.5～3cm)。其中单肺转移13例,双肺7例。原发病灶均有病理诊断,肺转移均经CT或MRI检查后临床诊断。利用计算机三维立体定向治疗计划系统(TPS)计算布源,在CT引导下将125I粒子植入肺转移病灶内。观察治疗后2个月病灶变化。结果20例56个病灶,完全缓解(CR)32个;部分缓解(PR)19个;无变化(NC)5个。总有效率91.1%。2个月内无死亡病例。发生气胸2例,咯血痰2例,胸腔出血1例,均经对症治疗后好转。结论胃肠道来源肺转移瘤,肺内病灶5个以下,最大直径不超过3cm,CT导向下125I粒子植入治疗,创伤小,并发症发生率低,近期效果好。
Objective To evaluate the short-term curative effect of CT-guided 125I seed implantation in patients with gastrointestinal metastases of pulmonary metastases. Methods Twenty patients with gastrointestinal metastases from the gastrointestinal tract were enrolled in this study. The total number of lesions was 56, with an average of 2.8 lesions per case. The average diameter of lesions was 2.1cm (0.5-3cm). One lung metastasis in 13 cases, 7 cases of lung. Primary lesions have pathological diagnosis, lung metastases by CT or MRI after the clinical diagnosis. The cloth source was calculated by computerized three-dimensional stereotactic planning system (TPS), and 125I seeds were implanted into lung metastasis lesion under CT guidance. Changes in lesions were observed 2 months after treatment. Results There were 56 lesions in 20 cases, with complete remission (CR) 32, partial remission (PR) 19 and no change (NC) 5. The total effective rate of 91.1%. No deaths within 2 months. 2 cases of pneumothorax occurred, 2 cases of hemoptysis sputum, 1 case of thoracic hemorrhage, all improved after symptomatic treatment. Conclusions There are less than 5 lung metastases in the gastrointestinal tract and no more than 3 lesions in the lung. The maximal diameter is no more than 3 cm. CT guided 125I seed implantation has the advantages of less trauma and lower complication rate.