论文部分内容阅读
目的:探讨妊娠相关乳腺癌的诊断和治疗。方法:对10例妊娠相关乳腺癌的临床及病理资料进行分析。结果:妊娠期发病6例,哺乳期发病4例。年龄23～37岁。所有病例术前均终止妊娠和哺乳,行乳腺癌根治术或改良根治术。术后病理报告均为浸润性导管癌,伴腋窝淋巴结转移,有6例雌/孕激素受体均阴性。术后病理TMN分期Ⅰ期2例,Ⅱ期2例,Ⅲ期5例,Ⅳ期1例。10例患者术后均予化疗。术后随访有2例患者术后10年仍存活,无腋淋巴结转移。5例死亡患者除1例淋巴结为2枚,其余均≥4枚。结论:妊娠相关乳腺癌因诊治晚,其预后较差。
Objective: To investigate the diagnosis and treatment of pregnancy-related breast cancer. Methods: The clinical and pathological data of 10 cases of pregnancy-related breast cancer were analyzed. Results: The incidence of pregnancy in 6 cases, 4 cases of breast-feeding. Age 23 to 37 years old. All cases were terminated before pregnancy and breast-feeding, radical mastectomy or modified radical mastectomy. Postoperative pathological reports were invasive ductal carcinoma, with axillary lymph node metastasis, 6 cases of estrogen / progesterone receptor were negative. There were 2 cases of stage Ⅰ TMN staging, 2 cases of stage Ⅱ, 5 cases of stage Ⅲ and 1 case of stage Ⅳ. Ten patients were treated with chemotherapy. Two patients were followed up after 10 years of survival, no axillary lymph node metastasis. 5 patients died except 1 patient with lymph node 2, the rest were ≥ 4 pieces. Conclusion: Pregnancy-related breast cancer has a poor prognosis due to late diagnosis and treatment.