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谷氨酸(glutamic acid,Glu)是一种拟议中的兴奋性神经递质。1969年 Olney 报道,外周注射大剂量谷氨酸—钠(monosodiumglutamate,MSG)可损伤动物下丘脑弓状核神经元。以后又对 MSG 的神经毒性作用进行了大量研究。这些研究推动了神经解剖学、神经内分泌学、神经生理学及神经精神病理学研究的发展。
Glutamic acid (Glu) is a proposed excitatory neurotransmitter. Olney in 1969 reported that peripheral injection of high doses of monosodium glutamate (MSG) can damage the hypothalamic arcuate nucleus neurons. After a large number of studies on the neurotoxic effect of MSG. These studies have contributed to the development of neuroanatomy, neuroendocrinology, neurophysiology and neuropsychopathology.