本文分析20年来用三种血管活性药物治疗重症流脑休克病儿的情况。经阿托品、异丙肾和多巴胺三种药物治疗,重症休克患儿的病死率分别为48.1%、31.1%、31.3%;总有效率分别为55.5%、70.5%、56.3%;以异丙肾组有效率最高,且付作用亦较小,认为值得一用。阿托品改善微循环见效最快,用药时间也最短。37例死亡病例中,有些病例死于休克纠正后的呼吸衰竭或/及肾功能衰竭。作者认为流脑休克病人的治疗应强调尽早和适当,防止RDS、肾功能衰竭和脑水肿;以望最终提高休克治疗的成功率。 This article analyzes the 20 years with three vasoactive drugs in children with severe brain disease meningitis. The treatment of atropine, isoproterenol and dopamine three drugs, children with severe shock mortality were 48.1%, 31.1%, 31.3%; the total effective rate was 55.5%, 70.5%, 56.3%; Isoproterenol group The most efficient and pay less is considered worthwhile. Atropine to improve microcirculation fastest, medication time is also the shortest. Of the 37 deaths, some died of shock-corrected respiratory failure or / and renal failure. The authors believe that the treatment of patients with meningitis should be emphasized as soon as possible and appropriate to prevent RDS, renal failure and cerebral edema; hope to eventually improve the success rate of shock treatment.