论文部分内容阅读
尽管随机研究显示对于稳定型冠心病(CHD),理想药物治疗(OMT)与血运重建同样有效,但实际临床工作中,OMT实施得并不理想。本研究旨在探索稳定型CHD患者接受OMT的预测因素以及对临床结局的影响。研究者纳入了2008年10月至2011年9月加拿大安大略省行冠状动脉造影的稳定型CHD,OMT定义为同时应用β受体阻断剂、血管紧张素转换酶抑制剂/血管紧张素受体拮抗剂和他汀类药物。由于数据库资料局限,阿司匹林不作为OMT的一部分。用多变量分层Logistic模型确定冠状动脉造影12个月后OMT的预测因素。
Although randomized studies have shown that ideal drug therapy (OMT) is as effective as revascularization for stable coronary heart disease (CHD), OMT does not perform well in clinical practice. The aim of this study was to investigate the predictors of OMT in patients with stable CHD and their impact on clinical outcomes. The investigators included a stable CHD with coronary angiography in Ontario, Canada, from October 2008 to September 2011. OMT was defined as a combination of beta-blocker, angiotensin converting enzyme inhibitor / angiotensin receptor Antagonists and statins. Aspirin is not part of the OMT because of limited database resources. Multivariate stratified Logistic model was used to determine predictors of OMT at 12 months after coronary angiography.