为10例多囊肾患者作经皮囊肿穿刺减压术,评价该方法对肾功能的影响。方法,穿刺术前后3天和1个月分别测定血清肌酐、尿素,尿酸,血红蛋白、红血球压积,肌酐清除率以及蛋白、β_2微球蛋白,N-乙酰氨基β_2-D葡萄糖甙酯。穿刺术前后分别测定菊粉、对氨基马尿酸清除率和~(99m)Tc-DMSA摄取量。硬膜外麻醉,在B超引导下用23号长针穿刺吸取囊肿液。结果,每个肾抽出液体112～968毫升,穿刺囊肿4～17个。血清肌酐、尿素氮、尿酸无明显变化。血红蛋白、红血球压积在穿刺术后三天明显下降,但 Percutaneous cyst puncture decompression was performed in 10 patients with polycystic kidney disease to evaluate the effect of this method on renal function. Methods Serum creatinine, urea, uric acid, hemoglobin, hematocrit, creatinine clearance and protein, β 2 microglobulin and N-acetyl-β 2-D glucoside were measured before and after 3 days and 1 month respectively. Inulin, p-aminomalanine clearance and ~ (99m) Tc-DMSA uptake were determined before and after puncture. Epidural anesthesia, using B-guided needle puncture with 23 long cyst fluid. As a result, 112 to 968 ml of fluid was withdrawn from each kidney and 4 to 17 puncture cysts. Serum creatinine, urea nitrogen, uric acid no significant change. Hemoglobin, hematocrit decreased significantly three days after puncture, however