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目的:研究与探讨清晨高血压伴2型糖尿病(MBPS-T2DM)对靶器官的影响。方法选择80例清晨高血压(MBPS)患者,其中对照组40例为单纯MBPS患者,观察组40例为MBPS-T2DM患者,比较两组患者血压、血脂及其他影响靶器官的相关指标。结果两组患者血压、血脂无显著性差异,无统计学意义(P>0.05);但观察组患者清晨血压升高值(IMBP)显著高于对照组,差异有统计学意义(P>0.05);观察组患者超敏C反应蛋白(hsCRP)、臂踝脉搏传导速度(baPWV)、颈动脉内膜中层厚度(IMT)、尿微量白蛋白(UAM)、左心室质量指数(LVMI)均显著高于对照组,差异有统计学意义(P>0.05)。结论MBPS-T2DM患者IMBP更高,且hsCRP、baPWV、IMT、UAM、LVMI均有显著上升,加重了患者动脉粥样硬化程度,对靶器官的损伤极大。
Objective: To study and explore the impact of early morning hypertension with type 2 diabetes mellitus (MBPS-T2DM) on target organs. Methods Eighty patients with early morning hypertension (MBPS) were enrolled in this study. Forty patients in the control group were simple MBPS patients and 40 in the observation group were MBPS-T2DM patients. Blood pressure, blood lipids and other target organs were compared between the two groups. Results There was no significant difference in blood pressure and blood lipids between the two groups (P> 0.05), but the IMBP in the observation group was significantly higher than that in the control group (P> 0.05) ; HsCRP, baPWV, IMT, UAM and LVMI in observation group were significantly higher than those in control group In the control group, the difference was statistically significant (P> 0.05). Conclusions The MBP-T2DM patients have higher IMBP, hsCRP, baPWV, IMT, UAM and LVMI, which increase the degree of atherosclerosis and cause great damage to target organs.