目的：将实验动物损伤时主要受损脏器的病理指标以积分表示，建立了实验动物病理中积分加权法。方法：本法在常规病理描述的基础上，对多脏器损伤的不同动物模型进行综合评价及甄别各受累脏器严重程度和疗效主评价。结果与结论：本法定量可靠，简便易行，不需要增加设备，易于推广。且有助于了解主要受损脏器以及药物作用对象与药物治疗效果，取得了良好的结果。 OBJECTIVE: Integrating the pathological indexes of the major damaged organs in experimental animals during injury, the integral weighting method was established in the pathology of experimental animals. Methods: On the basis of routine pathological description, this method comprehensively evaluated the different animal models of multiple organ injuries and screened the main evaluation of the severity and efficacy of the affected organs. Results and Conclusion: This method is quantitative and reliable, easy to operate, does not require additional equipment, easy to promote. And help to understand the main damage to organs and the role of drugs and drug treatment, and achieved good results.