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目的探讨中晚期直肠癌非手术的治疗方法。方法56例患者随机分成两组:(1)对照(A)组:单用动脉灌注化疗。(2)综合治疗组:采用动脉灌注化疗、栓塞同时用5-Fu、锡类散、云南白药等多因子灌肠治疗。两组病人均行两次介入治疗。结果A、B两组有效率,平均缓解期,中位生存期,1、2年生存率分别为32.7%、60.7%、2.8个月、5.1个月、6.5个月、11个月、32.7%、64.3%、3.6%、21.4%。两组差异均有显著性(P<0.05),临床症状改善两组也有显著性差异(P<0.05)。结论综合治疗可有效延长晚期直肠癌患者生存期,并改善其生存质量。
Objective To explore the non-surgical treatment of rectal cancer. Methods 56 patients were randomly divided into two groups: (1) Control (A) group: arterial infusion chemotherapy alone. (2) Comprehensive treatment group: arterial infusion chemotherapy, embolization and simultaneous treatment with 5-Fu, tin-like powder, Yunnan Baiyao and other multi-factor enema. Both groups of patients underwent two interventional treatments. Results The A and B groups were effective, the average remission period, median survival period, and 1-year survival rates were 32.7%, 60.7%, 2.8 months, 5.1 months, and 6. 5 months, 11 months, 32.7%, 64.3%, 3.6%, 21.4%. The differences between the two groups were significant (P<0.05), and there were also significant differences in clinical symptoms between the two groups (P<0.05). Conclusion Comprehensive treatment can effectively prolong the survival of patients with advanced rectal cancer and improve their quality of life.