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目的旨在探讨肥胖对新疆哈萨克族(哈族)和汉族正常血组组和高血压组左室重构和左心功能的影响。方法选取新疆昌吉地区哈族和汉族人群共550例,其中高血压组(EH)238例,正常血压组(NT)312例,根据亚太地区成人肥胖的界定标准(BMI≥25 kg/m~2),将所有受试对象分为肥胖组和非肥胖组,常规测量左室心肌质量(LVM)、左室心肌质量指数(LVMI)和E/A等超声指标。结果在NT组和EH组中,肥胖组的LVM、LVMI均高于非肥胖组。左室重构检出率也较非肥胖组增高,但E/A低于非肥胖组;哈汉两民族内,肥胖组的LVM、LVMI亦高于非肥胖组,但E/A低于非肥胖组。结论肥胖对新疆哈、汉两民族正常血压组和高血压组左室重构均具有影响,可引起左室舒张功能障碍。
Objective To investigate the effect of obesity on left ventricular remodeling and left ventricular function in Kazak (Kazakh nationality) and Han normal blood group and hypertension group in Xinjiang Autonomous Region. Methods A total of 550 Kazakh and Han nationalities in Changji district of Xinjiang were selected, including 238 hypertensive patients (EH) and 312 normal subjects (NT). According to the definition of obesity in adults in Asia Pacific region (BMI≥25 kg / m ~ 2 ). All the subjects were divided into obesity group and non-obese group, routine measurement of left ventricular mass (LVM), left ventricular myocardial mass index (LVMI) and E / A and other ultrasound indexes. Results In the NT group and EH group, LVM and LVMI in obese group were higher than those in non-obese group. The detection rate of left ventricular remodeling was also higher than that of non-obese group, but E / A was lower than non-obese group. LVM and LVMI of obesity group were higher than those of non-obese group Fat group. Conclusion Obesity affects both left ventricular remodeling and left ventricular remodeling in both Kazakh and Han nationality in Xinjiang and Xinjiang and may cause left ventricular diastolic dysfunction.