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血小板中环氧酶和脂氧酶作用于花生四烯酸代谢系统，可产生形成血栓的血栓烷Ａ２（ＴＸＡ２）及引起过敏性疾病的１２－羟基二十碳四烯酸（１２－ＨＥＴＥ）。ＴＸＡ２不稳定，迅速生成稳定的ＴＸＢ２，因此抑制ＴＸＢ２生成则可抑制血栓生成，抑制１２－ＨＥＴＥ生成则可预防动脉硬化及过敏性疾病。本文利用放射薄层方法，测定兔血中血小板花生四烯酸代谢产物ＴＸＢ２和１２－ＨＥＴＥ的生成量，筛选了４８种中药，其中２３味中药可选择性抑制环氧酶和脂氧酶的活性。浓度为１ｍｇ／Ｌ显示抑制作用强的中药有五倍子、柳叶，浓度为１０ｍｇ／Ｌ抑制作用较强的中药有桂皮、五倍子、茴香、黑加仑、蒲公英、甘草、车前草、柳叶等
Cyclooxygenases and lipoxygenases in platelets act on the arachidonic acid metabolism system, producing thromboxane A2 (TXA2) that forms a thrombus and 12-hydroxyeicosatetraenoic acid (12-HETE) that causes allergic diseases. TXA2 is unstable and rapidly generates stable TXB2. Therefore, inhibition of TXB2 production can inhibit thrombus formation, and inhibition of 12-HETE production can prevent arteriosclerosis and allergic diseases. In this paper, the production of TXB2 and 12-HETE metabolites of platelet arachidonic acid in blood of rabbits was determined by radio thin layer method. Forty-eight kinds of Chinese herbs were screened, of which 23 herbs could selectively inhibit the activity of cyclooxygenase and lipoxygenase. . The concentration of 1mg / L showed strong inhibition of Chinese gall nut, willow leaf, the concentration of 10mg / L strong inhibition of Chinese medicine has cinnamon, gallnut, fennel, black currant, dandelion, licorice, plantain, willow, etc.