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目的探讨拜新同对高血压脑梗死伴有抑郁状态的患者临床复发情况。方法对高血压脑卒梗死伴有抑郁状态的患者78例随机分两组,A组40例,B组38例。A组予拜新同降压,B组予用氨氯地平或洛丁新降压。其他治疗根据患者情况降糖、调脂、降同型半胱氨酸、抑血小板凝集、抗抑郁等治疗、房颤的患者予抗凝等治疗,观察两组患者3年内脑卒中复发情况进行对比。结果 A组脑卒中复发8例(其中1例患者未完成实验即死亡,故剔除此例患者),复发率20.5%,B组脑卒中复发13例,复发率36.1%,两者差异有统计学意义(P<0.05)。结论拜新同对高血压脑卒中伴抑郁状态患者较其他降压药有明显的降低其复发率。
Objective To explore the clinical recurrence of patients with hypertension and cerebral infarction who are worshiped by Xinxin. Methods 78 patients with hypertensive cerebral infarction with depression were randomly divided into two groups: 40 cases in group A and 38 cases in group B. A group to worship new with antihypertensive, B group with amlodipine or luoding new buck. Other treatment according to the patient’s hypoglycemic, lipid-lowering, homocysteine, platelet aggregation, antidepressant treatment, atrial fibrillation patients with anticoagulant therapy, observed two groups of patients with recurrent stroke were compared within 3 years. Results A group of stroke recurred in 8 cases (1 patient died in the experiment did not complete, so remove the patient), the recurrence rate was 20.5%, B group 13 cases of recurrent stroke, the recurrence rate was 36.1%, the difference was statistically Significance (P <0.05). Conclusion Baixin with hypertension stroke patients with depression compared with other antihypertensive drugs significantly reduce the recurrence rate.