论文部分内容阅读
目的通过对脑实质神经鞘瘤的影像学表现及相关病理分析,提高该病的诊断准确率,有利于手术方案的制定及患者的预后。方法回顾性分析4例经手术病理及免疫组织化学证实的脑实质神经鞘瘤。其中1例行 CT 平扫及增强检查,1例行 MR 平扫,2例行 CT 及 MR 平扫+增强扫描,并结合文献进行分析。结果 4例中,3例年龄小于30岁,均位于幕上;均出现囊变征象,3例出现壁结节,3例增强者中壁结节呈明显强化2例,中度强化1例;1例壁结节内见钙化征象,1例周边水肿明显;病理上均见 Antoni A 区、B 区;免疫组织化学检查,酸性钙结合蛋白(S100)、波形蛋白(Vim)阳性,胶质纤维酸性蛋白(GFAP)、上皮膜抗原(EMA)阴性。结论脑实质神经鞘瘤好发于青少年,囊变及周围水肿为其特征性表现,结合病理及免疫组织化学检查有利于最终确诊。
Objective To improve the diagnostic accuracy of the parenchyma schwannoma by imaging features and related pathological analysis, which is beneficial to the development of surgical plans and the prognosis of patients. Methods Retrospective analysis of 4 cases of pathological and immunohistochemical confirmed parenchyma schwannoma. Among them, 1 case had plain and enhanced CT scan, 1 case had MR plain scan, 2 cases had CT and MR plain scan + enhanced scan, and analyzed with literature. Results Among the 4 cases, 3 cases were younger than 30 years old, all of them were located on the screen. Cystic signs were found in all cases. Wall nodules occurred in 3 cases. Mural nodules in 3 cases were significantly enhanced in 2 cases and moderately enhanced in 1 case. One case of intracranial nodules showed signs of calcification and one case of peripheral edema was obvious. The pathological findings were seen in the areas of Antoni A and B; immunohistochemistry, S100, Vim and glial fibrils Acid protein (GFAP), epithelial membrane antigen (EMA) negative. Conclusion Cerebral parenchymal nerve sheath tumors occur in adolescents, cystic changes and surrounding edema as its characteristic manifestations, combined with pathology and immunohistochemistry is conducive to the final diagnosis.