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目的探讨阿托品化指标量化观察在有机磷中毒救治中应用价值。方法 93例有机磷中毒患者分为实验组43例和对照组50例,分别以阿托品量化指标和常规阿托品化临床表现指导阿托品的应用。比较两组痊愈时间、阿托品总用量和阿托品中毒、有机磷中毒反跳发生率。结果实验组痊愈时间(8.2±4.9)d快于对照组(13.3±4.7)d,阿托品总用量(83.6±81.7)mg少于对照组(301.2±99.3)mg,阿托品中毒发生率(4.65%)及反跳率(0)均低于对照组12.00%、4.00%。结论阿托品化指标量化观察能减少阿托品用量、阿托品中毒和反跳的发生,缩短病程。
Objective To investigate the value of quantitative observation of atropine in the treatment of organophosphate poisoning. Methods A total of 93 patients with organophosphate poisoning were divided into experimental group (n = 43) and control group (n = 50). Atropine was used to guide the administration of atropine and its clinical manifestations. The recovery time of two groups was compared, the total amount of atropine and atropine poisoning, the incidence of organophosphate poisoning rebound. Results The recovery time of experimental group (8.2 ± 4.9) d was faster than that of control group (13.3 ± 4.7) d, the total amount of atropine (83.6 ± 81.7) mg was less than that of control group (301.2 ± 99.3) mg and the incidence of atropine poisoning was 4.65% And rebound rate (0) were lower than the control group 12.00%, 4.00%. Conclusions Quantification of atropisol indicators can reduce the amount of atropine, atropine poisoning and rebound, shorten the course of the disease.