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贲门失弛症(AC),是一食管、贲门神经、肌肉运动功能障碍性疾病。患者进食吞咽时,食管体部缺乏有推动力的蠕动,贲门括约肌不能松弛,食物不能通过贲门入胃,而潴留于食管内。临床表现吞咽困难、呕吐、胸痛、胸闷、营养不良、消瘦乏力等症状。其治疗的关键是使贲门松弛,目前有下述7种方法。 1药物治疗 消心痛、硝苯吡啶、硫氮(艹卓)草酮、解痉灵和654-2等,每次餐前20～30分钟口服或舌下含化。均可暂时性松弛贲门括约肌,缓解吞咽困难等症状。若一旦停药,症状即又复现,难以治愈。药物治疗作用时间短,不能阻止病情进展,必须长期餐前服药,有副作用等缺点,只宜作辅助治疗。
Cardiac achalasia (AC), is an esophagus, cardia, motor dysfunction disease. When patients eat and swallow, the body of the esophagus lacks motivating motility, the cardia sphincter can not relax, and the food can not enter the stomach through the cardia and stay in the esophagus. Clinical manifestations of dysphagia, vomiting, chest pain, chest tightness, malnutrition, weight loss and other symptoms. The key to its treatment is to cardia relaxation, there are seven methods below. 1 drug treatment of heartburn, nifedipine, sulfur nitrogen (Zhuo Zhuo) konjac, antispasmodic and 654-2 and so on, each oral or sublingual 20 to 30 minutes before meals. Can temporarily relax cardia sphincter, relieve symptoms such as dysphagia. Once the withdrawal, the symptoms that reproduce, it is difficult to cure. Short duration of drug treatment, can not stop the progress of the disease, must be long-term pre-meal medication, side effects and other shortcomings, should only be used as adjuvant therapy.