近年来,由于分子生物化学的发展,对辅酶Q_(10).(简称COQ_(10))的研究愈来愈多,特别是其在疾病治疗中的临床地位也与日俱增的引起了人们的兴趣,现将近年来国内外对COQ_(10).研究应用情况作一概述,供同道参考.1940年Moore等首次发现动物体中的COQ_(10).存在后,引起了人们对COQ_(10).兴趣,1957年Crane等证实COQ_(10)是一种氧化一还原载体,在哺乳动物的细胞呼吸中起着重要作用的辅酶.1965年由Yamamura等首次应用COQ_(10)治疗心血管疾病.1970年 In recent years, due to the development of molecular biochemistry, the research on coenzyme Q_ (10) (COQ_ (10) for short) has been more and more, especially its clinical status in the treatment of diseases has also caused the people’s interest. In recent years, the research and application of COQ_ (10) in China and abroad have been summarized at home and abroad for reference.Recently, COO_ (10) in animal body has been discovered by Moore et al. , 1957 Crane et al confirmed that COQ_ (10) is an oxidoreductase and plays an important role in the cellular respiration of mammalian coenzyme. In 1965, COQ_ (10) was first applied to treat cardiovascular diseases by Yamamura et al.