患者男,34岁,因不规则上腹隐痛3年、柏油便2天于1992年4月15日入院。查体无异常。白细胞5.56×10~9/L,大便潜血(++++)。予以西米替丁0.4g每日一次静点,3天后用量增至0.6g,5天后又增为0.8g。7天后大便潜血(一),停用西米替丁。用药期间白细胞计数分别为3.0×10~9/L、3.1×10~9/L、3.8×10~9/L、2.5×10~9/L 及2.4×10~9/L。停药1周后白细胞计数1.8×10~9/L,血色素、血小板正常。急行髂骨穿刺做骨髓检查,显示粒系增生减低、细胞形态正常。停药后给其口服 Vit B_4 Male patient, 34 years old, due to irregular upper abdominal pain for 3 years, 2 days of asphalt was admitted on April 15, 1992. No abnormalities in the examination. WBC 5.56 × 10 ~ 9 / L, fecal occult blood (++++). To cimetidine 0.4g once daily static point, 3 days after the dosage increased to 0.6g, 5 days later increased to 0.8g. 7 days after the fecal occult blood (a), disable cimetidine. The white blood cell counts during treatment were 3.0 × 10 ~ 9 / L, 3.1 × 10 ~ 9 / L, 3.8 × 10 ~ 9 / L, 2.5 × 10 ~ 9 / L and 2.4 × 10 ~ 9 / L, respectively. 1 week after stopping the white blood cell count 1.8 × 10 ~ 9 / L, hemoglobin, platelets normal. Implantation of iliac bone marrow examination done, showing reduced myeloid hyperplasia, normal cell morphology. After stopping taking it orally Vit B_4