1978年第一次报道了雄性大鼠和男子使用从棉子中提取的黄色酚类化合物棉酚的抗生育作用。以后证明棉酚在一些中国人中引致低血钾症。因为醛甾酮对调节钾的排泄非常重要,因此测定用棉酚处理过的大鼠血清钾和醛甾酮。因为棉酚对血清睾酮的作用还有争论,因而也测定血清睾酮水平。鉴于血清 T_3、T_4与控制生长及代谢有关,也加以测定。给两组各8只雄性 Sprague Dawley 大鼠,通过食道插管,将30mg/kg 棉酚混悬在 The first anti-fertility effect was reported in 1978 in male rats and men using the yellow phenolic compound gossypol extracted from cottonseed. Gossypol later proved to cause hypokalemia in some Chinese. Because aldosterone is very important for regulating potassium excretion, serum potassium and aldosterone in gossypol-treated rats were determined. Because of the controversy over the effect of gossypol on serum testosterone, serum testosterone levels are also measured. In view of serum T_3, T_4 and control of growth and metabolism, also be measured. Two groups of eight male Sprague Dawley rats each were suspended by esophageal cannulation with 30 mg / kg gossypol