论文部分内容阅读
脓毒症是接受复杂腹部外科手术以及外伤或灼伤病人的重要死因,目前主要采用支持疗法和抗生素治疗。以针对内毒素或脂多糖(LPS)分子核心区的抗体治疗的临床试验结果表明,这种治疗对脓毒症有效。美国马里兰大学医学院Cross制备了脱毒大肠杆菌J5LPS(J5dLPS)B群脑膜炎球菌外膜蛋白(
Sepsis is an important cause of death in patients undergoing complicated abdominal surgery and trauma or burns. At present, the majority of patients are treated with supportive therapy and antibiotics. Clinical trials with antibodies directed against the core of endotoxin or lipopolysaccharide (LPS) molecules have shown that this treatment is effective in sepsis. Cross prepared from detoxified Escherichia coli J5LPS (J5dLPS) group B meningococcal outer membrane protein