过去的很多研究表明:间充质干细胞也是一种力学敏感细胞,力学刺激对间充质干细胞的分化和生长有重要影响,间充质干细胞经5-氮胞苷诱导可分化为心肌或心肌样细胞。本研究为探索力学刺激对间充质干细胞向心肌细胞分化的影响而进行。体外分离培养Wistar大鼠脂肪组织来源的间充质干 Many studies in the past have shown that mesenchymal stem cells are also mechano-sensitive cells, and mechanical stimuli have an important influence on the differentiation and growth of mesenchymal stem cells. Mesenchymal stem cells can be induced to differentiate into myocardium or myocardium by 5-azacytidine cell. This study was conducted to explore the effect of mechanical stimulation on the differentiation of mesenchymal stem cells into cardiomyocytes. Mesenchymal stem cells derived from adipose tissue of Wistar rats were isolated and cultured in vitro