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链霉素对微生物的作用的研究表明,链霉素有可能作为选育的诱变因子。本文研究制霉菌素产生菌153(Act.noursei 153)菌株经链霉素处理后在形态和产制霉菌素能力方面的变异。实验结果表明,随着抗菌素浓度的提高,制霉菌素产生菌153的孢子存活率下降。当链霉素浓度为10单位/毫升时,存活率为39.9%;剂量为80单位/毫升时,存活率仅为0.043%。存活率同剂量的关系表现为递减的指数特点。在淀粉-氨琼脂培养基上研究了制霉菌素产生菌153的2000多个菌落,并按其大小、形状、颜色、
Studies on the effect of streptomycin on microorganisms have shown that streptomycin may be used as a mutagen in breeding. In this paper, the variation of morphology and nystatin-producing ability of Streptomycin-producing strain 153 (Act.noursei 153) after streptomycin treatment was studied. The experimental results showed that the spore survival rate of nystatin-producing bacteria 153 decreased with the increase of antibiotic concentration. Survival rate was 39.9% at a streptomycin concentration of 10 units / ml and only 0.043% at a dose of 80 units / ml. The relationship between survival and dose showed a decreasing index. More than 2000 colonies of nystatin-producing bacteria 153 were studied on starch-ammonia agar medium, and their size, shape, color,