论文部分内容阅读
应用酶联免疫吸附试验（ＥＩＬＳＡ）对３０例扩张型心肌病（ＤＣＭ）患儿和４０例健康儿童进行了抗心磷脂抗体（ＡＣＡ）测定，包括ＡＣＡ－ＩｇＧ、ＡＣＡ－ＩｇＡ和ＡＣＡ－ＩｇＭ；ＤＣＭ患儿同时检查肌酸磷酸激酶心肌同功酶（ＣＫ－ＭＢ）、心电图、多普勒超声心动图。结果：ＤＣＭ患儿ＡＣＡ各类阳性率均显著高于健康儿童（Ｐ＜０．０１），ＡＣＡ总阳性率为８０％；ＡＣＡ阳性者的ＳＴ－Ｔ改变发生率、心腔扩大率和左室收缩功能降低率均显著高于ＡＣＡ阴性者，而ＡＣＡ与ＣＫ－ＭＢ、左室舒张功能无关。认为ＡＣＡ对ＤＣＭ有重要诊断价值，并有助于判断其病情轻重
Serum anticardiolipin antibodies (ACA), including ACA-IgG, ACA-IgA and ACA-IgM, were measured in 30 DCM children and 40 healthy children by enzyme-linked immunosorbent assay (EILSA) DCM children were also examined creatine phosphokinase myocardial isoenzyme (CK-MB), ECG, Doppler echocardiography. Results: The positive rates of ACA in DCM children were significantly higher than those in healthy children (P <0.01), and the positive rate of ACA was 80%. The incidence of ST-T changes, The reduction rate of systolic function was significantly higher than that of ACA negative, while ACA was independent of CK-MB and left ventricular diastolic function. That ACA DCM has important diagnostic value, and help determine the severity of the disease