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本文用固相放射免疫法(SPRIA)、酶标法(ELISA)和反向被动血凝法(RPHA)栓测了49例慢性乙肝炎患者的血清病原学感染指标,发现各种不同方法之间敏感性具有差异。其中39例慢活肝组HBeAg阳性17例,抗—HBe阳性9例,10例慢迁肝中HBeAg阳性5例,抗—HBe阳性1例。分析了各项乙型肝炎病毒感染指标的意义,提出单用HBsAg评位有无传染性和药物疗效是不确切的;慢活肝患者有较高的HBeAg阳性病例,是值得重视的传染因素。
In this paper, serum etiological markers of 49 patients with chronic hepatitis B were determined by solid phase radioimmunoassay (SPRIA), enzyme-linked immunosorbent assay (ELISA) and reverse passive hemagglutination (RPHA), and found that between different methods Sensitivity is different. Of the 39 patients, 17 were HBeAg-positive, 9 were anti-HBe, 5 were HBeAg-positive and 1 was anti-HBe in 10 slow-moving liver. The significance of each index of hepatitis B virus infection was analyzed. It is inaccurate to propose whether the use of HBsAg alone or not and the curative effect of HBsAg alone. The patients with chronic liver failure have higher HBeAg positive cases, which is an infectious factor worthy of attention.