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选择42例空腹血脂正常的T2DM患者,行75gOGTT测定空腹及服糖后2hPG、血脂、纤维蛋白原(Fg),同时放免法测定胰岛素(INS)、C肽(CP)水平,并于18例正常人做对比。结果:①空腹及2hPG升高(P<0.01);②空腹及服糖后甘油三酯(TG)升高(P<0.05);③2hCP、计算HOMAβ细胞分泌指数(IS)降低(P<0.05,P<0.01);④空腹Fg升高(P<0.05)结论:DM组虽然空腹TG在正常范围内,但已经存在脂代谢紊乱、高凝血低纤溶的病理状态,胰岛分泌功能受损。
Forty-two patients with T2DM with fasting serum lipids were selected, and 75gOGTT was used to measure the fasting and 2hPG, lipids and fibrinogen (Fg) after fasting, and the insulin (INS) and C peptide (CP) People make contrast. The levels of triglyceride (TG) and fasting plasma glucose (TG) were increased (P <0.05); ③2hCP, the HOMAβsecretion index (IS) was decreased (P <0.05, (P <0.01) .④The fasting Fg increased (P <0.05) Conclusion: Although the fasting TG in the DM group is within the normal range, the disorder of lipid metabolism and hypercoagulability and fibrinolysis exist in the DM group, and the islet secretion is impaired.