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目的:探讨超敏C反应蛋白(hs-CRP)和D二聚体(D-D)对腔隙性脑梗死早期的诊断价值。方法:将63例通过CT确诊腔隙性脑梗死的病人分为单纯腔隙性脑梗死组(A组)、合并高血压或糖尿病组(B组)及同时合并高血压、糖尿病组(C组);选择20名非脑血管病病人作为对照组(D组)。所有病人于起病24 h内抽血,采用免疫比浊法对hs-CRP和D-D进行测定。结果:腔隙性脑梗死病人hs-CRP和D-D明显高于对照组,同时合并高血压和糖尿病的病人尤其明显。结论:hs-CRP和D-D可作为腔隙性脑梗死早期辅助诊断的指标。
Objective: To investigate the diagnostic value of hs-CRP and D-D in early diagnosis of lacunar infarction. Methods: Sixty-three patients with lacunar infarction diagnosed by CT were divided into two groups: group A (lacunar infarction), group B (hypertension) and diabetes mellitus (group B), and group C ); 20 non-cerebrovascular patients were selected as control group (D group). All patients were drawn blood within 24 h of onset, and hs-CRP and D-D were measured by immunoturbidimetry. Results: The patients with lacunar infarction hs-CRP and D-D was significantly higher than the control group, especially in patients with hypertension and diabetes mellitus. Conclusion: hs-CRP and D-D can be used as early diagnosis of lacunar infarction.