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用放射免疫分析法测定了人和大鼠血浆神经降压素样免疫活性物质(NTLI)的含量。结果表明,酶抑制剂(抑肽酶和杆茵肽)可使血浆 NTLl 测值明显增大;进食也可使血浆 NTLI 含量显著增加(P<0.05);间情大鼠血浆 NTLI 的含量较动情期降低极显著(P<0.01)。因此,在抗凝血中加入酶抑制剂确能提高血浆 NTLI 的测定值。
Radioimmunoassay was used to determine plasma levels of neurotensin-like immunoreactive substance (NTLI) in humans and rats. The results showed that the enzyme inhibitors (aprotinin and rod-intima) can significantly increase the measured value of plasma NTL1; the content of plasma NTLI also increased significantly (P <0.05); the content of NTLI in plasma Period decreased significantly (P <0.01). Therefore, the addition of an enzyme inhibitor to anticoagulants does improve the measurement of plasma NTLI.