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基底动脉供血不足（ＶＢＩ）的前庭功能变化至今有争议，为探讨此问题将脑缺血豚鼠分为３组，术前及术后６ｈ、１２ｈ、２４ｈ测视动眼震（ＯＫＮ）及正弦摆动前庭性眼震（ＳＰＶＮ）。结果：（１）颈总动脉结扎前后ＳＰＶＮ无变化，而ＯＫＮ术侧眼震频率下降，与健侧比有统计学差异；证明脑缺血时视动功能比前庭功能更易受损；（２）颈总动脉加同侧推动脉结扎组，除术侧ＯＫＮ频率下降外，ＳＰＶＮ频率亦下降（Ｐ＜０．０５），术后１２ｈＯＫＮ、ＳＰＶＮ恢复至术前水平，证明阻塞一侧脑血管首先影响同侧之ＯＫＮ、ＳＰＶＮ，受损与缺血之程度呈正相关；（３）左颈总动脉加双侧椎动脉结扎组双侧ＯＫＮ、ＳＰＶＮ频率下降，缺血重侧受损明显，两侧有差异，术后２４ｈ尚不能恢复。证明ＶＢＩ时可出现ＯＫＮ、ＳＰＶＮ的改变。
Vestibular function changes of basilar insufficiency (VBI) have been controversial so far. To explore this issue, guinea pigs with cerebral ischemia were divided into 3 groups. OKN and sinusoidal oscillations were measured preoperatively and 6h, 12h, 24h after operation Vestibular nystagmus (SPVN). Results: (1) There was no change in SPVN before and after common carotid artery occlusion, but the nystagmus frequency in OKN decreased significantly compared with that in contralateral side. It was proved that visual acuity was more vulnerable than vestibular function in cerebral ischemia. The carotid artery plus ipsilateral artery ligation group, in addition to OKN frequency decreased, the SPVN frequency also decreased (P <0.05), 12 hours afterOKN, SPVN returned to preoperative levels, showing that the first side of the occlusion of cerebral blood vessels affect Ipsilateral OKN, SPVN, the degree of damage and ischemia was positively correlated; (3) bilateral left common carotid artery plus bilateral bilateral ligation of OKN, SPVN frequency decreased, significant damage to the ischemic side of the severe, both sides have Difference, still can not recover after 24h. Prove VBI can appear OKN, SPVN changes.