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宫颈癌作为女性高发的妇科恶性肿瘤,缺乏有效的早期诊断技术、治疗方法。蛋白质组学是研究蛋白质组成和动态变化的新兴学科,现在已经广泛应用于肿瘤生物学标记物的筛选和鉴定、治疗疗效的评价及肿瘤发生机制等方面的研究。现就蛋白质组学的研究技术在宫颈癌组织蛋白表达中的应用,化疗药物作用机制等方面的进展综述。
Cervical cancer as a high incidence of gynecological malignant tumors, the lack of effective early diagnosis and treatment methods. Proteomics is a new discipline that studies the composition and dynamics of proteins. Now it has been widely used in the screening and identification of tumor biomarkers, the evaluation of therapeutic effects and the mechanisms of tumorigenesis. Now on the application of proteomics research in cervical cancer tissue protein expression, mechanism of action of chemotherapy drugs and so on.