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目的探讨口服甘露醇对急性胰腺炎的治疗作用。方法将72胰腺炎患者随机分为两组,对照组用常规治疗(禁食、胃肠减压、维持水电解质平衡、保持血容量、营养支持、抗炎、抑酸、减少胰腺分泌、对症、支持)。治疗组在常规治疗基础上加用甘露醇口服。两组均观察外周血中白细胞(WBC)及分类中的中性粒细胞(N)、血淀粉酶(BAMS)、尿淀粉酶(UAMS)、血糖等指标变化。结果治疗组各项指标与对照组,其差异有高度显著性(P<0.01)。结论口服甘露醇对轻症急性胰腺炎有很好的辅助治疗作用。
Objective To investigate the therapeutic effect of oral mannitol on acute pancreatitis. Methods 72 pancreatitis patients were randomly divided into two groups. Patients in the control group were treated with conventional therapy (fasting, decompression of gastrointestinal tract, maintaining water and electrolyte balance, maintaining blood volume, nutritional support, anti-inflammatory, acid suppression, reducing pancreatic secretion, symptomatic, stand by). The treatment group was treated with mannitol orally on the basis of routine treatment. Peripheral blood leukocytes (WBC) and classification of neutrophil (N), blood amylase (BAMS), urinary amylase (UAMS), blood glucose and other indicators were observed in both groups. Results There was a significant difference between the treatment group and the control group (P <0.01). Conclusion oral mannitol has a very good adjuvant therapy for mild acute pancreatitis.