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目的:观察葆宫止血颗粒辅助左炔诺孕酮宫内节育器系统(曼月乐宫内节育器)治疗异常子宫出血的疗效。方法:按自愿原则将异常子宫出血患者分为2组,对照组41例单纯宫内放置曼月乐宫内节育器,实验组43例放置曼月乐宫内节育器后,有阴道出血时即口服葆宫止血颗粒,比较2组患者治疗后前3个月经周期的有效率及治疗前后的血红蛋白值、子宫内膜厚度及经期天数。结果:治疗3个周期后,实验组有效率为97.67%,对照组有效率为85.37%,2组比较,差异有统计学意义(P<0.05)。2组治疗后第1月、2月、3月的子宫内膜厚度比较,差异均无统计学意义(P>0.05)。实验组治疗后第1月、2月、3月的血红蛋白值均高于对照组,但差异均无统计学意义(P>0.05)。实验组治疗后第1月、2月的经期天数均较对照组缩短,差异均有统计学意义(P<0.05);治疗后第3月时,实验组经期天数少于对照组,但差异无统计学意义(P>0.05)。2组均有3例患者出现不良反应。结论:葆宫止血颗粒辅助曼月乐宫内节育器和单纯使用曼月乐宫内节育器治疗异常子宫出血均疗效显著、安全,不良反应少;葆宫止血颗粒在异常子宫出血的治疗中有明确辅助作用。
Objective: To observe the curative effect of Baogan Zhixue granule-assisted levonorgestrel IUD (Mirena IUD) in treating abnormal uterine bleeding. Methods: According to the voluntary principle, patients with abnormal uterine bleeding were divided into two groups. In the control group, 41 cases received intrauterine Mirena Ileotherapy alone. In the experimental group, 43 cases received Mirena IUD after vaginal bleeding Oral Bao granule hemostatic particles were compared two groups of patients after treatment the first three menstrual cycle efficiency and before and after treatment of hemoglobin value, endometrial thickness and the number of days. Results: After three cycles of treatment, the effective rate of the experimental group was 97.67% and that of the control group was 85.37%. There was significant difference between the two groups (P <0.05). There was no significant difference in endometrial thickness between the two groups after 1 month, 2 months and 3 months (P> 0.05). The hemoglobin value of the experimental group in January, February and March after treatment was higher than that of the control group, but the difference was not statistically significant (P> 0.05). In the experimental group, the days of menstruation in the first month and the second month of treatment were both shorter than those in the control group (P <0.05). At the third month after the treatment, the number of menstrual periods in the experimental group was less than that in the control group, but the difference was no Statistical significance (P> 0.05). Three patients in both groups experienced adverse reactions. Conclusion: Baogan Zhixue granule supplemented with Mirena IUD and Mirena alone used in treatment of abnormal uterine bleeding were significant efficacy, safety, adverse reactions less; Baogan hemostatic particles in the treatment of abnormal uterine bleeding A clear supporting role.