论文部分内容阅读
目的比较经尿道前列腺等离子双极电切术(PKRP)与经尿道前列腺电切术(TURP)两种术式治疗良性前列腺增生对性功能的影响。方法计算机检索Medline、Embase、Web of Science及CNKI电子数据库,查找所有比较PKRP和TURP治疗良性前列腺增生症的随机对照试验(RCT),检索时限为建库至2015年10月。同时手检纳入文献的参考文献。按纳入、排除标准由两人独立进行RCT的筛选、资料提取和质量评价,应用RevMan 5.2软件对符合纳入标准的文献资料进行Meta分析。结果共纳入10个研究、1408例患者,其中PKRP组704例,TURP组704例。Meta分析结果显示,与TURP比较,PKRP术后勃起功能障碍发生率明显降低[OR=0.51,95%CI(0.36,0.74),P<0.01],但逆行性射精[OR=0.51,95%CI(0.36,0.74),P<0.01,精液量减少[OR=0.66,95%CI(0.18,2.41),P>0.05],差异无统计学意义。结论 PKRP和TURP两种术式比较,PKRP术后勃起功能障碍发生率明显降低,对逆行性射精、精液量减少的发生率的影响无差别。
Objective To compare the effects of transurethral prostatectomy (PKRP) and transurethral resection of the prostate (TURP) on benign prostatic hyperplasia (BPH) on sexual function. Methods A computer-based online search of Medline, Embase, Web of Science and CNKI databases was conducted to find out all the randomized controlled trials (RCTs) comparing PKRP with TURP in the treatment of benign prostatic hyperplasia. At the same time hand-checked into the literature reference. According to the inclusion and exclusion criteria, two individuals independently conducted screening, data extraction and quality evaluation of RCTs. Meta-analysis was performed on the documents that met the inclusion criteria using RevMan 5.2 software. Results A total of 10 studies and 1408 patients were enrolled. Of these, 704 were in the PKRP group and 704 in the TURP group. Meta-analysis showed that the incidence of erectile dysfunction after PKRP was significantly lower than that of TURP [OR = 0.51,95% CI (0.36,0.74, P <0.01], but retrograde ejaculation [OR = 0.51,95% CI (0.36,0.74), P <0.01, the amount of semen decreased [OR = 0.66,95% CI (0.18,2.41), P> 0.05], the difference was not statistically significant. Conclusion Compared with PKR and TURP, the incidence of erectile dysfunction after PKRP was significantly decreased, but there was no difference between the two groups in the incidence of retrograde ejaculation and semen volume reduction.