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迄今国内外对原发性肾病综合征(PNS)的治疗,仍为肾上腺皮质激素(激素)及激素联合免疫抑制剂两大类疗法。近年来,对激素疗程的长短,疗效优劣,尚有争论,激素联合免疫抑制剂疗效如何?也未最后定论。本文分析56例小儿PNS的治疗情况,结合临床、随访结果,并就激素联合免疫抑制剂治疗难治性肾病的疗效进行探讨。1 一般资料.男39例,女17例,男:女=2.3:1;发病年龄<2岁5例(8.93%),2~5岁21例(37.50%),5岁以上30例(53.57%)。单纯性肾病(SNS)40例,肾炎性肾病(NNS)16例。属难治性肾病8例。
So far at home and abroad for the treatment of primary nephrotic syndrome (PNS), still adrenal cortex hormones (hormones) and hormones combined immunosuppressive two broad categories of therapies. In recent years, the length of hormone therapy, the pros and cons of the effect, there are still controversy, hormonal combination immunosuppressive effect? No final conclusion. This article analyzes the treatment of 56 cases of pediatric PNS, combined with clinical, follow-up results, and hormone combination immunosuppressive agents in the treatment of refractory renal disease were investigated. There were 39 males and 17 females, male: female = 2.3: 1; age of onset was less than 2 years old in 5 cases (8.93%), age ranged from 2 to 5 years (37.50%), age over 5 was 30 years %). 40 cases of simple nephrotic syndrome (SNS) and 16 cases of nephritic nephropathy (NNS). Is a refractory renal disease in 8 cases.