氯霉素(CAP)目前仍在临床广泛应用,但它是药物引起的再生障碍性贫血的主要原因。1949年开始用CAP后,Volini等首先报告CAP引起可逆的红细胞系统抑制,其特点是。早期红细胞成熟停滞和出现空泡,网织红细胞减少以及铁动力学的改变,后者表示红细胞系统造血受抑制。1950年Rich等报导了 Chloramphenicol (CAP) is still widely used clinically, but it is the main cause of drug-induced aplastic anemia. After CAP began in 1949, Volini et al. First reported that CAP caused reversible inhibition of erythrocyte system, which is characterized by. Early red blood cell maturation stagnation and the emergence of vacuoles, reticulocyte reduction and changes in iron dynamics, the latter said the hematopoietic system of red blood cells inhibited. Rich et al. Reported in 1950