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二次脑损伤(SBI)也称继发性脑损伤,即是在已有脑原发性损伤的基础上,因某些因素的改变(如血压、脑温、颅内压、脑血流及脑灌注压),进一步加重了原发的脑损害。近年来,大量研究发现:脑损伤后脑局部出现的炎症反应是二次脑损伤的机制之一,IL-1β是主要的致炎性因子,具有触发炎症?
Secondary brain injury (SBI), also known as secondary brain injury, that is, already in the primary brain injury, based on changes in certain factors (such as blood pressure, brain temperature, intracranial pressure, cerebral blood flow and Cerebral perfusion pressure), further aggravating the primary brain damage. In recent years, a large number of studies have found that the brain inflammatory response after brain injury is one of the mechanisms of secondary brain injury. IL-1β is the main inflammatory factor that triggers the inflammation.