新生儿期感染性疾病特别是败血症缺乏特异症状及体征,易与其他疾病相混淆,而其诊断一贯有赖血培养证实,但血培养阳性率不高且耗时较长,不能达到早期诊断的目的。70年代中期一些快速特异性诊断方法如对流免疫电泳、乳胶颗粒凝集试验等相继问世,仅数分钟或数小时即可得出结果,但因新生儿病原 Neonatal infectious diseases, especially sepsis, lack of specific symptoms and signs, and other diseases easily confused, and its diagnosis has always been confirmed by blood culture, but the positive rate of blood culture is not high and takes a long time, can not achieve the purpose of early diagnosis . In the mid-1970s, some rapid and specific diagnostic methods such as convective immunoelectrophoresis and latex particle agglutination test were published one after another, only in a few minutes or hours to get the result, but due to neonatal pathogens