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本文报告单用苯妥因治疗31例(14～72岁)新近有2次或更多次癫痫发作但从未治疗的门诊患者。其中特发性大发作17例,病灶性大发作4例,病灶性大小发作与小发作各5例。平均随访14.7个月。随访时无1例有进展性病灶损害证据。每例最初服苯妥因200或300毫克/日,分2次,其后每次就诊(视发作控制程度而定,每2周～3个月1次)均测定血清苯妥因浓度。若尚未控制发作,则增加苯妥因剂量到血清最适水平(10～20微克/毫升);若仍有1次或多
This article reports the use of phenytoin alone in 31 patients (14-72 years) who have had two or more seizures but never treated outpatients. Among them, 17 were idiopathic major episodes, 4 were major episodes, and 5 were focal episodes and minor episodes. The average follow-up was 14.7 months. None of the patients had evidence of progressive lesion at follow-up. In each case, the initial dose of phenytoin was 200 or 300 mg / day in 2 batches, and every subsequent visit (depending on the degree of seizure control, once every 2 weeks to 3 months) measured the concentration of phenytoin in the serum. If you have not yet control seizures, increase the dose of phenytoin to the serum optimal level (10 ~ 20 micrograms / ml); if there is still 1 or more