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动脉粥样硬化 (ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ,ＡＳ)是严重危害人类健康的疾病 ,糖尿病患者并发ＡＳ的可能性是正常人的 3～ 4倍。高血糖状态下蛋白质发生的非酶糖基化可使其最终形成不可逆的糖基化终产物 (ａｄｖａｎｃｅｄｇｌｙｃｏｓｙｌａｔｉｏｎｅｎｄｐｒｏｄｕｃｔ
Atherosclerosis (atherosclerosis, AS) is a serious disease of human health, diabetic patients with the possibility of AS is 3 to 4 times the normal. Non-enzymatic glycation of proteins under hyperglycemic conditions can eventually lead to the formation of irreversible advanced glycosylation end products