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目的初步探讨空腹血糖和糖化血红蛋白用于筛查糖尿病的临床意义,并探讨空腹血糖和糖化血红蛋白的相关性。方法选择我院门诊2011年12月至2012年12月为明确糖尿病而就诊者及糖尿病高危人群筛查者556例,均进行糖化血红蛋白(HbA1C)及空腹血糖(FPG)检测,对得出的数据进行统计处理,并分析不同FPG与HbA1C的相关性。结果 FPG高于6.1mmol/L为62例,HbA1C高于6%者为69例,分别占总人数的11.15%和12.41%,而FPG和HbA1C中任一指标出现异常者为91例,筛出率为16.37%;不同FPG与HbA1C的相关性分析:FPG为(6.99±1.83)mmol/L,HbA1C为(7.41±2.29)%,两者相关系数r=0.567,P=0.015。结论 FPG与HbA1C关系密切,联合检测FPG与HbA1C对早期糖尿病高危人群的筛查有重要意义。
Objective To investigate the clinical significance of fasting blood glucose and glycosylated hemoglobin in the screening of diabetes mellitus, and to explore the correlation between fasting blood glucose and glycosylated hemoglobin. Methods From December 2011 to December 2012 in our hospital, 556 cases of patients with diabetes and high risk of diabetes were enrolled. HbA1C and FPG were detected. The data obtained Statistical analysis was performed and the correlation between different FPGs and HbA1C was analyzed. Results Sixty-two patients with FPG higher than 6.1mmol / L and 69 patients with HbA1C higher than 6% accounted for 11.15% and 12.41% of the total, respectively. However, 91 patients with abnormal FPG or HbA1C abnormality were screened out The association rate of different FPG with HbA1C was (6.99 ± 1.83) mmol / L and (7.41 ± 2.29)%, respectively. Correlation coefficient between them was r = 0.567, P = 0.015. Conclusion FPG is closely related to HbA1C. The combined detection of FPG and HbA1C is of great significance in the screening of high-risk population of early-stage diabetes.